Sara Salazar

POSITION: PhD Student

RESEARCH THEME: Yeast-based synthetic biology

E-mail: sara.salazar@tecnico.ulisboa.pt

Research Topics

  • Mechanisms of antifungal drug resistance in Candida glabrata, in particular those mediated by the CgPdr1 transcription factor
  • Role of the CgHaa1 regulatory system in pathogenesis and stress response of Candida glabrata
  • Unravel adaptive mechanisms of C. glabrata to the human host through comparative genomics

Selected Publications

Salazar SB, Wang C,
Munsterkotter M, Okamoto M, Takahashi-Nakaguchi A, Chibana H, Lopes MM,
Guldener U, Butler G and Mira NP, Comparative genomic and transcriptomic
analyses unveil novel features of azole resistance and adaptation to the human
host in Candida glabrata, FEMS Yeast Res, 17, (2017)(in press)

Bernardo R, Cunha DV, Wang C, Pereira L, Silva S, Salazar SB, Schroeder MS, Okamoto M, Takahashi-Nakaguchi A, Chibana H, Aoyoama T, Sá-Correia I, Azeredo J, Butler G and Mira NP, The CgHaa1-regulon mediates response and tolerance to acetic acid stress in the human pathogen Candida glabrata, G3: Genes, Genomes and Genetics, 7: 1-18, (2017)

Cunha D*, Salazar SB*, Lopes MM and Mira NP, Mechanistic insights underlying tolerance to acetic acid stress in vaginal Candida glabrata isolates, Frontiers in Microbiology, 8: 259 (2017)(*co-first authors)